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May 18, 2023 / Amgen - Job Posting Title Sr. Associate Scientist (Biophysical Characterization)

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Job Posting Title Sr. Associate Scientist (Biophysical Characterization)

Job Posting Title Sr. Associate Scientist (Biophysical Characterization)

Posting Details

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Job Description


You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Sr Associate Scientist (Biophysical Characterization)

What you will do

Let’s do this. Let’s change the world. In this vital role you will join our affinity team in In Vitro Pharmacology group to discover novel therapeutic antibodies.

Our small team specializes in designing and conducting both high throughput and smaller, custom biophysical screening assays to rank and characterize both discovery and later stage large molecule therapeutic programs. The individual will join a team of dedicated scientists to discover and characterize molecules that have the potential to help patients in need. A well-suited applicant will have great laboratory skills, a strong analytical mindset, deep scientific curiosity, and a can-do attitude. The successful candidate will be responsible for the development, optimization, and implementation of various biophysical based screening assays for novel therapeutic candidates with guidance from the lead Scientist.

This is a permanent role that offers potential for advancement and career development. Successful candidates must reside in the Greater Vancouver area.

If you have a passion for science and want to be part of an organization discovering new medicines that will impact patients’ lives, we invite you to join us!

Essential Functions:
Conduct both routine and novel affinity/kinetic characterization screens on all relevant platforms (Carterra, Octet, Biacore), including custom assays (reagent QC, R/L, chain bins, epitope bins) and help develop new methods
Instrument housekeeping like regular desorbs, needle/injector block/slide cleans, etc.
Support with quants when the primary quant role is away (<20% of time)
Data summarizing and reporting using various internal platforms (ELN, Screener, HTB/Benchling, slide decks for internal review)

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The highly motivated professional we seek is a collaborative team player with these qualifications.

Basic Qualifications:
Doctorate degree


Master’s degree & 3 years of related experience


Bachelor’s degree & 5 years of directly related experience

Preferred Qualifications:
Deep understanding of molecular binding interaction theory (SPR, BLI) and associated fitting models
Firsthand experience with various SPR platforms and the associated instrumentation nuances – specifically Biacore (any model, but 3000 experience is desirable)
A good understanding of protein chemistry and/or a general biochemistry background; antibody specific experience desired
A keen eye and a strong analytical mindset, with an interest and aptitude for DoE tasks like assay development and /or troubleshooting
Ability to multitask and stay organized in the face of shifting priorities

What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and annual company-wide shutdown
Flexible work models, including remote work arrangements, where possible
Apply now
for a career that defies imagination

Objects in your future are closer than they appear. Join us.

How to Apply

Application Deadline: 31/07/2023

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